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Gastroenterology and Hepatology

at Princess Alexandra Hospital

The Department of Gastroenterology and Hepatology at the Princess Alexandra Hospital was established in 1968 and is today an integral part of the hospital, providing specialised diagnostic, endoscopic and consultative services for patients with disorders of the digestive tract and the liver.

With state of the art diagnostic and interventional endoscopic services, clinicians and support staff provide specialised assessment and gastrointestinal functional testing complementing the treatment of patients with gastrointestinal problems. Specialised departmental staff have been heavily involved with the Queensland Liver Transplant Service since the first liver transplant in Australia in 1985. The department has close clinical links with the upper gastrointestinal, colorectal and hepatopancreato-biliary surgical units.

In recent years, there has been an accelerated drive to enhance the strong research focus in the department. Research laboratories are co-located on the PAH campus in the Translational Research Institute (TRI), one of the largest medical research institutes in the Southern Hemisphere.

Gastroenterology and Hepatology team

Consultant Staff from left to right: Dr Daniel Burger, Dr Caroline Tallis, Dr Nadia Maqboul, Dr Neal Martin, Dr Ashok Raj, Dr Luke Hourigan, Dr Lara Kane, Professor Gerald Holtmann, Dr Katherine Stuart, Dr Bradley Kendall, Dr Terrence Tan, Dr Saurabh Gupta, Professor Elizabeth Powell, Associate Professor Dr Graeme Macdonald, Dr Paul Clark, Dr Rebecca Ryan (absent).

Gastroenterology and Hepatology Staff

Director
Professor Gerald Holtmann, MD, PhD, MBA, FRACP, FRCP

Clinical Director Endoscopy
Dr Luke Hourigan, MBBS, FRACP

Director of Hepatology
Dr Katherine Stuart, PhD, MBBS, FRACP

Consultant Staff
Dr Daniel Burger, BSc, MBBS (Hons), FRACP
Dr Paul Clark, PhD, MBBS, FRACP
Dr Saurabh Gupta, MBBS, (Hons), FRACP
Dr Lara Kane, MBBS, FRACP
Dr Bradley Kendall, MBBS, FRACP
Associate Professor Dr Graeme Macdonald, PhD, MBBS, FRACP
Dr Neal Martin, BSc, MBBS, FRACP
Dr Nadia Maqboul, MBBS, BSc (Hons), MPH, FRACP
Professor Elizabeth Powell, PhD, MBBS (Hons), FRACP, FRCP (Lond)
Dr Ashok Raj, FRACP, MBChB
Dr Rebecca Ryan, BMBS (Hons) FRACP
Dr Caroline Tallis, BPhty (Hons), MBBS (Hons), FRACP
Dr Terrance Tan, PhD, MBBS, FRACP

Interventional Endoscopy Fellow
Dr Andrew St John, BSc/BA, MBBS, FRACP

IBD/MotiliIty Fellow
Dr Natalie Kiel, BSc, MBBS

Advanced Trainees in Gastroenterology and Hepatology
Dr Peter Hendy, BSc, MBBS
Dr Graeme Rich, MBBS, BMedSci

Hepatology and Liver Transplant Fellow
Dr James Thomas, BM, BSc (Hons), MRCP (UK)

Senior Scientist
Associate Professor Linda Fletcher, PhD, BSc (Hons)

Research Fellows
Dr Kevin Fagan, BSc, BM (Hons), MRCP (UK)
Dr Aidan Woodward,  B.Pharm, MBBS

Research and Clinical Trial Coordinator
Dr. Natasha Koloski, PhD

Data Manager & Quality  Manager
Dr. Marguerite Kutyla, BPharm (Hons) PhD

Translational Research Institute (TRI)
Gastroenterology and Hepatology Laboratories

Office Manager
Ms Jenny Scott

Clinical Services

Gastroenterology

  • Gastrointestinal motility and functional disorders
  • Inflammatory bowel disease
  • Gastrointestinal cancers
  • Gastrointestinal bleeding disorders
  • Peptic ulcer and reflux disease
  • Malabsorption
  • Pancreatic and biliary disorders
  • Interventional endoscopy with emphasis on biliary and pancreatic diseases.

Hepatology

  • Liver transplantation
  • Cirrhosis
  • Chronic viral hepatitis
  • Hepatocellular carcinoma
  • Metabolic liver diseases
  • Non-alcoholic fatty liver disease (NAFLD)
  • General hepatology
  • Liver biopsy, Transient elastography, Indocyanine green testing, Shear wave elastography.

Inpatient Services

Acute Inpatient Care

The Department of Gastroenterology and Hepatology has 20-25 inpatient beds for the management of patients with specialised gastrointestinal and hepatobiliary problems. It has a dedicated liver transplant hepatology service and 24/7 cover for GI emergencies including ERCP and interventional endoscopy.

Consultative Service

The Department provides consultative service to other medical and surgical units at the Princess Alexandra Hospital. Requests for consultations should be arranged through the Gastroenterology Registrar or resident, who can be contacted through the Hospital switchboard on (07) 3176 2111.

Outpatient Services

Gastroenterology Clinic

Clinics are held for patients with general gastroenterological problems as well as for inflammatory bowel diseases, motility or functional gastrointestinal disorders and pancreato-biliary diseases. In addition, Specialised Gastroenterology and Hepatology clinics have been established for a number of disease conditions including:

  • General Gastroenterology
  • Inflammatory Bowel Disease
  • Gastrointestinal Motility Disorders
  • Interventional Endoscopy.

Hepatology Clinics

The Hepatology section of the Department offers an extensive outpatient program focusing on patients with chronic viral hepatitis, cirrhosis, hepatocellular cancer, metabolic liver diseases and non-alcoholic fatty liver disease (NAFLD). The Department is a major referral centre in Queensland for patients with hepatocellular carcinoma and is an accredited viral hepatitis treatment centre. Specialised pre-liver transplant clinics are also held. We have on offer several methods of non-invasive assessment of liver disease including FibroScan® and shear wave elastography.

Patients with liver disease can be referred to the Hepatology clinics which are held at the Burke Street Treatment Centre. These clinics provide for the integrated management of patients with liver disease in close liaison with the Hepatobiliary Surgical Unit, The Alcohol and Drug Unit and Psychiatric Services, as required. Member of the Department have extensive experience with the whole spectrum of antiviral therapies for chronic viral hepatitis and frequently can provide their patients access to innovative new treatments within defined clinical studies before they become routinely available.

The General Hepatology clinics are attended by Dr Katherine Stuart, Associate Professor Graeme Macdonald, Professor Elizabeth Powell, Dr Lara Kane, Dr Rebecca Ryan, Dr Caroline Tallis and Dr Paul Clark.

Patients with the following problems can be referred to this Clinic:

  • Abnormal liver tests
  • Alcohol related liver disease 
  • Chronic viral Hepatitis B and C infection
  • Cirrhosis and its complications
  • Focal liver lesions including hepatocellular cancer
  • Abnormal iron studies
  • Drug induced liver disease 
  • Ascites / Portal hypertension.

Liver Transplant Clinics

Several Hepatologists are senior members of the Queensland Liver Transplant Service and work closely with their liver transplant surgical colleagues. Pre-liver transplant assessment, integrated post-liver transplant and Hepatoma clinics are held at the Burke Street Treatment centre. The hepatobiliary surgeons attending these clinics include Professor Jonathan Fawcett, Dr Peter Hodgkinson and Dr David Lockwood.

Gastrointestinal Investigation Unit

Endoscopy

  • Interventional Endoscopy Assessment Clinic
  • Upper and lower Endoscopy
  • ERCP and interventions
  • Endoscopic ultrasound and related interventions
  • Endomucosal resection of polyps and early mucosal tumours (Endoscopic submuccosal dissections) 
  • Capsule and balloon enteroscopy
  • Stent placements and placement of Sleeve devices
  • Percutaneous Endoscopic Gastrostomies/Jejunostomies (PEG/PEJ).

Motility and Gastrointestinal Function Testing

  • Oesophageal manometry
  • Ambulatory oesophageal pH monitoring
  • Hydrogen Breath testing for small bowel bacterial overgrowth and lactose intolerance 
  • 13C Breath testing (using IRIS) for gastric emptying, pancreatic function, H. pylori colonisation 
  • Post-prandial oesophageal manometry and pH monitoring
  • Anorectal manometry.

Endoscopy Diagnostic and Therapeutic Procedures

The Endoscopy Unit provides the following diagnostic and therapeutic procedures:

Diagnostic procedures

  • Upper gastrointestinal endoscopy
  • Capsule and balloon enteroscopy
  • Colonoscopy and sigmoidoscopy (flexible and rigid) 
  • Endoscopic ultrasound and guided biopsy
  • Endoscopic retrograde cholangio pancreatography (ERCP).

Liver Specific Assessment

  • Liver biopsy
  • Liver elasticity measurements (FibroScan® and Shear wave elastography)
  • Determination of hepatic reserve for the assessment of liver function incorporating FibroScan®, Indocyanine green (ICG) and 13C methacetin breath tests.

Therapeutic procedures

  • Oesophageal dilatation 
  • Variceal sclerotherapy/banding 
  • Gastric variceal glue
  • Oesophageal stenting 
  • Ulcer injection 
  • Polypectomy 
  • Argon plasma coagulation 
  • Removal of foreign bodies 
  • Diathermy 
  • Percutaneous endoscopic gastrostomy and jejunostomy (PEG/PEJ)
  • Gastric or enteric feeding tubes 
  • Abdominal paracentesis 
  • Haemorrhoid treatment
  • Endoscopic sphincterotomy – CBD stone removal
  • Biliary or pancreatic stent insertion
  • Biliary or pancreatic stricture dilation
  • Biliary electrohydraulic lithotripsy
  • Colo-rectal stricture dilation
  • Enteral stent insertion.

A number of Gastroenterologists and Hepatologists have the expertise and special interest in providing care for patients with the following conditions:

  • Gastrointestinal motility and functional disorders
    Prof Gerald Holtmann, Dr Daniel Burger, Dr Neil Martin
  • Inflammatory bowel disease
    Prof Gerald Holtmann, Dr Daniel Burger, Dr Neil Martin
  • Barrett’s Oesophagus: Dr Bradley Kendall
  • Hepato-pancreato-biliary disorders and interventional endoscopy
    Dr Luke Hourigan, Dr Saurabh Gupta, Prof Gerald Holtmann
  • Liver transplantation: Dr Katherine Stuart, Associate Professor Graeme  Macdonald, Dr Rebecca Ryan, Dr Caroline Tallis
  • Hepatocellular cancer: Dr Katherine Stuart.

Gastrointestinal Investigations

The Department provides state-of-the-art endoscopic services including endoscopic ultrasound and cholangioscopy, and manometric assessment for oesophageal disorders.

Endoscopic Diagnostic and Therapeutic Procedures

  • Upper and lower endoscopy
  • ERCP and interventions
  • Endoscopic ultrasound and related interventions
  • Endoscopic mucosal resection of polyps and early mucosal tumours
  • Capsule and balloon enteroscopy
  • Resection of large gastric & colonic lesions
  • Endoscopic treatment of varices
  • Endoscopic treatment of Barrett’s lesions 
  • Argon plasma coagulation of mucosal lesions
  • Percutaneous endoscopic gastrostomy (PEG)
  • Colorectal stricture dilation 
  • Placement of oesophageal, duodenal or colonic stents.

Motility and Functional Testing

The Department provides comprehensive services in the field of motility and GI function testing. The procedures include:

  • Oesophageal manometry
  • Ambulatory oesophageal pH monitoring
  • Wireless Capsule pH-Metry (BRAVO)
  • Post-prandial oesophageal manometry and pH monitoring
  • Anorectal manometry (is done in collaboration with the QE11 Hospital)
  • Endo-anal ultrasound.

Student Teaching

Medical students of The University of Queensland are regularly attached to the Unit. International students may apply via the University of Queensland. Other Students are offered placements (e.g. TPN for pharmacists) based upon the availability of slots.

Training

The Department of Gastroenterology and Hepatology is fully accredited with the Royal Australasian College of Physicians for advanced training in Gastroenterology and Hepatology. There are two advanced clinical training registrar positions each year. In addition, there is a third year Fellow position in the field of Gastrointestinal Motility/IBD, a position for an Interventional Endoscopy Fellow and a position for a Hepatology Fellow. Opportunities for further training exist for national or international applicants if they are funded or can attract at least part of the funding.

Direct your expression of interest in writing to either of the following:

Gastroenterology and Clinical/Translational Research

Professor Gerald Holtmann
Email: Gerald.Holtmann@health.qld.gov.au

Hepatology

Dr Katherine Stuart
Email: Katherine.Stuart@health.qld.gov.au

Basic and Translational Research in Hepatology

Professor Elizabeth Powell
Email: e.powell@uq.edu.au

Interventional Endoscopy

Dr Luke Hourigan
Email: Luke.Hourigan@health.qld.gov.au

Research

The Department of Gastroenterology and Hepatology has a strong research track record. The collocated Translational Research Institute provides and outstanding opportunity and has a stellar international reputation that attracts trainees and senior investigators from overseas. Members of the Department have laboratory space in this facility and we have created a hospital-research laboratory pipeline where research samples are collected during specialised procedures and transported to the research laboratories for cutting edge experimentations which will ultimately lead to new treatment options.

A number of research projects related to various aspects of Gastroenterology and Hepatology are currently conducted in our Department, including drug therapies for functional and inflammatory bowel diseases, pathophysiology of functional gastrointestinal disorders, efficiency and safety of interventional endoscopic techniques, drug therapies for viral hepatitis and pathophysiological mechanisms of non-alcoholic steatohepatitis, liver repair and regeneration and innate immune function in chronic liver disease.

Basic scientific experimental research is conducted at adjacent Translational Research Institute and research collaborations exist with the QIMR Berghoffer Medical Research Institute (QIMR) and Centre for Advanced Imaging, University of Queensland.

Specific Research Projects

Specific research projects with lead investigators in the field of Gastroenterology and Hepatology include:

FieldLead investigators and contact details
Epidemiology and pathophysiology of functional gastrointestinal disordersProfessor Gerald Holtmann
Gerald.Holtmann@health.qld.gov.au
Drug therapies in Functional and inflammatory related Gastrointestinal disordersProfessor Gerald Holtmann
Neuroimmune GI disordersProfessor Gerald Holtmann
Gastrointestinal microbiomeProfessor Gerald Holtmann and Dr Erin Shanahan
e.shanahan@uq.edu.au
Nutrition and GI motilityProfessor Gerald Holtmann
Reflux disease and complications including Barrett's oesophagusDr Bradley Kendall
Bradley.Kendall@health.qld.gov.au
Endobarrier in obesity and metabolic diseaseDr Saurabh Gupta and Dr Graeme Rich
Saurabh.Gupta@health.qld.gov.au
Graeme.Rich@health.qld.gov.au
Interventional endoscopy, ERCP, endoscopic ultrasound, EMR/ESD, large colonic polypectomy, Barrett's endotherapy and palliative stent placementDr Luke Hourigan
Luke.Hourigan@health.qld.gov.au
Monocytes/macrophages in chronic liver injury characterizing the ascites microbiomeProfessor Elizabeth Powell
e.powell@uq.edu.au
Evaluation of serum markers of liver injuryDr Kate Irvine
katharine.irvine@uq.edu.au
Models of care and health outcomes in chronic liver diseaseProfessor Elizabeth Powell
Predictors of hepatic decompensation after surgical therapy of hepatocellular cancerDr Katherine Stuart and Dr Caroline Tallis
Katherine.Stuart@health.qld.gov.au
Caroline.Tallis@health.qld.gov.au
Epidemiology and natural history of hepatocellular cancer and assessment of treatment responseDr Katherine Stuart
Katherine.Stuart@health.qld.gov.au
Population approaches to liver cancer epidemiologyDr Paul Clark
Paul.Clark@health.qld.gov.au
Intestinal gut permeability and gut microbiota in the pathogenesis of chronic liver diseaseAssociate Professor Graeme Macdonald and Dr Ashok Raj
Graeme.Macdonald@health.qld.gov.au
Ashok.Raj@health.qld.gov.au
Assessment of muscle mass hepatic function and outcome in patients awaiting liver transplantationAssociate Professor Graeme Macdonald and Dr Aidan Woodward
Graeme.Macdonald@health.qld.gov.au
Aidan.Woodward@health.qld.gov.au
Molecular mechanisms of progressive liver injury pertaining to iron, alcohol and fat as hepatic co-toxinsAssociate Professor Linda Fletcher and Dr Terrance Tan
Linda.Fletcher@health.qld.gov.au
Terrance.Tan@health.qld.gov.au
Proteins of iron metabolism as predictors of outcome following liver transplantationAssociate Professor Linda Fletcher

Staff Profiles

Professor Gerald Holtmann, MD, PhD, MBA, FRACP, FRCP

Professor Gerald Holtmann is the Director of The Department of Gastroenterology & Hepatology and Associate Dean Clinical at The University of Queensland.

Professor Holtmann has a clinical interest in functional and neuro-immune mediated gastrointestinal disorders. He contributes to clinical services in particular by contributing to endoscopic services (endoscopy, colonoscopy, ERCP), the provision of motility services and invasive and non-invasive function testing.

His research interests focus on the field of Neurogastroenterology and he has continuously attracted peer reviewed funding from national and international funding bodies such as the National Health and Medical Research Council (NHMRC), and the German Research Foundation. He has published more than 300 articles and book chapters in leading journals including the NEJM, Lancet and Gastroenterology.

Professor Holtmann completed his Clinical Training in Medicine and Gastroenterology at the University Hospital Essen, Germany and the Mayo Clinic, Rochester, MN. He is a Fellow of The Royal College of Physicians (London) and The Royal Australasian College of Physicians. In addition to his training in Medicine and Gastroenterology he completed a Master of Business Administration at the University of South Australia and is certified by the German Board of Physicians in Medical Informatics and Biostatistics. Since his relocation to Brisbane in 2011, he has focused on redesigning Gastroenterology and Hepatology clinical service delivery to allow greater integration of clinical and translational research. He is now working to further develop translational and basic research to improve diagnosis and treatment of patients with gastrointestinal disorders.

Dr Luke Hourigan, MBBS, FRACP

Dr Luke Hourigan is the Clinical Director of Endoscopy at Princess Alexandra Hospital, Brisbane. His clinical leadership responsibilities include clinical management of PAH Endoscopy and supervision of the Interventional Endoscopic Fellow. His areas of expertise include ERCP, endoscopic resection of early upper GI and colonic neoplasia (including endoscopic submucosal dissection), Barrett’s endotherapy, palliative stent placement and endoscopic ultrasound.

Dr Hourigan completed his advanced training in Gastroenterology and Hepatology at the Mater Hospital and Princess Alexandra Hospital, Brisbane (1996-1998). He completed postgraduate training in Interventional Endoscopy at Westmead Hospital, Sydney and St Michael’s Hospital (Wellesley), Toronto (1999-2001).

Luke has been an invited speaker and proceduralist at national and international meetings. He has been an active member of GESA (Gastroenterological Society of Australia) including several terms as a committee member of AGEA (Australian Gastrointestinal Endoscopy Association). He is a past President of the GE Society of Queensland.

Areas of endoscopic research interest include endoscopic resection of early gastrointestinal malignancy, ERCP and Barrett’s endotherapy.

Dr Katherine Stuart, PhD, MBBS, FRACP

Dr Katherine Stuart, an eminent Brisbane Hepatologist, has been the Director of Hepatology at Princess Alexandra Hospital since 2009 and is a senior member of The Queensland Liver Transplant Service. Following graduation from The University of Queensland’s MBBS program, Katherine trained in Gastroenterology and Hepatology at the Mater Adult and Royal Brisbane Hospitals, before spending a year in London with Professor Roger Williams. Upon returning to Brisbane she was the Hepatology Liver Transplant Fellow at the Princess Alexandra Hospital before embarking on a PhD investigating the Mechanisms and Significance of Iron Accumulation in Cirrhosis. Katherine was the Director of Physician Training at the Princess Alexandra Hospital between 2003 and 2007. She has been an invited speaker at national and local meetings and was a member of the Australian Liver Association, Executive Committee from 2006 to 2013. Katherine is in private practise at Greenslopes Private Hospital and is a member of the Clinical trials unit at the Gallipoli Medical Research Foundation. Her research interests include epidemiology of hepatocellular carcinoma, role of co-factors in cirrhosis and hepatocellular cancer, assessment of liver function in cirrhosis and viral hepatitis.

Dr Daniel Burger, BSc, MBBS (Hons), FRACP

Dr Burger is a Staff Specialist Gastroenterologist with a sub-specialty interest in Inflammatory Bowel Diseases (IBD), Crohn’s Disease and Ulcerative Colitis. He is also a Gastroenterologist with the Wesley Hospital Gastroenterology and Liver Group Dan completed a Bachelor of Science degree at The University of Queensland before enrolling in a medical degree at Flinders’ Medical School, South Australia where he graduated with Honours and the Chancellors Letter of Recommendation from in 2001. He undertook physician training at the Royal Brisbane and Women’s Hospital (RBWH) in Brisbane and completed his gastroenterology specialist training at both the Mater Adult Hospital and RBWH.

Dr Burger spent two years as the Senior Clinical Fellow at The John Radcliffe Hospital, Oxford UK in 2012. He is currently as staff specialist at the Princess Alexandra Hospital where he has established a comprehensive IBD service including research and specialist registrar training.

Dr Paul Clark, PhD, MBBS (Hons), MPH & TM, FRACP

Dr Paul Clark graduated from medicine at The University of Queensland with First Class Honours. He undertook gastroenterology training at the Royal Brisbane and Women's Hospital and the Princess Alexandra Hospital, and fellowship training at the Duke University Medical Center in the Unites States.

In addition to his role at the Princess Alexandra Hospital, Paul also provides public outreach clinical services to the Inala Indigenous Health Service, Rockhampton Viral Hepatitis Clinic (via tele health), and an "in-reach" program for women with hepatitis C incarcerated at Brisbane Womens' Correctional Centre.

Paul has a concurrent appointment with the QIMR Berghofer Medical Research Institute supported by a NHMRC Early Career Health Practitioner Fellowship exploring linkages between hepatitis epidemiology and liver cancer treatment and diagnosis in Queensland. He is a Board Member of Hepatitis Queensland, the Australian Liver Foundation and a member of the Executive Committee of the Australian Liver Association.

Dr Saurabh Gupta, BSc (Med), MBBS (Hons), FRACP

Dr Saurabh Gupta is a Gastroenterologist specialising in advanced diagnostic and therapeutic endoscopy. Dr Gupta performs endoscopic ultrasound, ERCP, endoscopic mucosal resection of advanced neoplasia and enteroscopy. He has a special interest in pancreatic malignancies, focussing on early diagnosis and endoscopic pain management.

Dr Gupta graduated with Honours from the University of New South Wales (Sydney, Australia) before undertaking his Fellowship in Gastroenterology. After completing this in 2007, Dr Gupta spent time in Brisbane and at Duke University Medical Center, (North Carolina, USA) undertaking further training in ERCP and endoscopic ultrasound.

Dr Gupta is a Senior Lecturer with the University of Queensland, and works as a Senior Staff Gastroenterologist at the Princess Alexandra Hospital and Visiting Gastroenterologist at The Wesley Hospital. He has participated in national live-endoscopy workshops and presented research at several national and international meetings.

Dr Lara Kane, MBBS, FRACP

Dr Lara Kane is a graduate of The University of Queensland. She completed her Gastroenterology and Hepatology training at The Princess Alexandra Hospital and The Mater Hospitals, Brisbane. On completion of her specialty training she had the opportunity to gain clinical and research experience through the Newcastle-upon-Tyne Hospitals NHS Trust, England. She further completed a subspecialty fellowship in Hepatology and Liver transplantation at the Princess Alexandra Hospital. She currently provides Gastroenterology and Hepatology services and is involved in junior medical staff training.

Dr Bradley Kendall, MBBS, FRACP

Dr Brad Kendall is a Senior Staff Gastroenterologist at The Princess Alexandra Hospital and a Senior Lecturer at the University of Queensland. After advanced training at the Royal Brisbane Hospital, he underwent post fellowship training at the University of Virginia and the University of California – Los Angeles. He then returned as a Visiting Gastroenterologist at the RBWH where he worked until taking up his current position in 2007.

In collaboration with researchers at the QIMR Berghofer Medical Research Institute, he is actively involved in Barrett’s oesophagus research having published in international journals on the subject. He is part of the Cancer Council Australia working party developing clinical guidelines for the management of Barrett's oesophagus. He is actively involved in undergraduate and post-graduate medical training and is a former President of the Gastroenterological Society of Queensland and a past member of the Australian Digestive Health Foundation of the Gastroenterology Society of Australia.

Associate Professor Graeme Macdonald, PhD, MBBS, FRACP

Associate Professor Macdonald is a Senior Staff Specialist in the Department of Hepatology and Gastroenterology, and a member of the Queensland Liver Transplant Service. His clinical interests are predominantly in liver disease and he provides clinical services in general hepatology, and the care of patients pre- and post liver transplantation. He also provides a telehealth service to treat prisoners with liver disease in SE Queensland; and runs a clinical trials unit that undertakes industry-sponsored studies of investigational agents for use in liver disease, particularly hepatitis C.

His research interests are in obesity-related liver injury and liver transplantation and he has received peer-reviewed funding from the National Health and Medical Research Council, the Cancer Council of Queensland, and other funding bodies. He has supervised 10 higher degree students and has published over 80 articles and book chapters in the area of liver disease.

Dr Neal Martin, BSc, MBBS, FRACP

Dr Neal Martin is a full time Staff Gastroenterologist at The Princess Alexandra Hospital. He underwent advanced training in gastroenterology and hepatology in Queensland, following which he travelled to London for an IBD Fellowship at the Royal London and St Bartholemew’s hospitals. On his return to Brisbane in 2011, he established the Inflammatory Bowel Disease and Motility Clinic and the IBD Hot Clinic.

Currently Dr Martin is involved in the IBD/Motility Clinic and the Intestinal Failure and IBD Hot Clinics. He is responsible for the IBD inpatients, as well as a weekly inpatient TPN round and also the Home Parenteral Nutrition patients. He participates in endoscopy and colonoscopy as well as Bowel Screening colonoscopy and capsule endoscopy. Dr Martin is involved in Registrar and Fellow teaching, and participates in the QGEP lecture series with a focus on IBD.

Dr Nadia Magboul, MBBS, BSc (Hons), MPH, FRACP

Dr Nadia Maqboul is a Staff Specialist Gastroenterologist with a sub-specialty interest in Interventional Endoscopy.

Nadia obtained her medical degree at the Royal Free and University College Medical School, London. She was subsequently employed at The Royal Free Hospital and Luton and Dunstable Hospital, UK, after which she moved to Melbourne to embark on Basic Physician Training and Specialist Training in Gastroenterology. During this time she was awarded the Inaugural Neville Yeomans Prize for the best Medical Research. Dr Maqboul went on to spend two years as the Interventional Fellow at The Princess Alexandra Hospital in 2012.

Nadia has also completed a BSc (Hons) and a Masters in Public Health; the results of her research project were used to try and highlight areas of health-care need amongst ethnic minority populations in the North of England.

Currently, Dr Maqboul participates in endoscopy and colonoscopy, (including screening colonoscopy for the National Bowel Cancer Screening Programme), as well as more advanced endoscopic procedures such as ERCP, EUS, single balloon enteroscopy and EMR of colonic polyps. Dr Maqboul is also involved in Fellow and Registrar teaching.

Professor Elizabeth Powell, MBBS, FRACP, PhD

Professor Elizabeth Powell is an eminent Staff Specialist/Hepatologist at The Princess Alexandra Hospital and Director of the Centre for Liver Disease Research, The University of Queensland within the Translational Research Institute. She has a clinical interest in obesity-related liver disease, chronic viral hepatitis and complications of cirrhosis, conditions that are responsible for the increasing burden of liver disease.

Her research interests focus on the importance of metabolic risk factors in the progression of chronic liver diseases, and more recently the role of altered hepatic regeneration and the ductular reaction as a potential driver of hepatic fibrosis. Her group has a strong track record in successful NHMRC Project Grant funding and in fostering health and medical research training. She has been working to develop a partnership with primary care clinicians to address the urgent need for new strategies to assess and treat chronic liver disease and improve patient access to appropriate care.

Professor Powell currently holds an NHMRC Practitioner Fellowship (third renewal) and has been awarded a Queensland Government Health Research Fellowship. She is a member of the Editorial Board of Hepatology (ranked as the number 1 Hepatology journal), a recent past member of the Clinical Research Committee of the American Association for the Study of Liver Diseases and a current member of the Executive of the Australian Liver Association, the key national body responsible for actively engaging and contributing to government policy on technology and treatment pertinent to liver disease.

Dr Ashok Raj, FRACP, MBChB

Dr Raj is a Staff Specialist in the Department of Hepatology and Gastroenterology, and a PhD scholar at the Translational Research Institute, University of Queensland. He is a medical graduate of The University of Auckland, New Zealand. He undertook specialty training in Gastroenterology and Hepatology working in tertiary hospitals in Auckland and Brisbane, where he developed a major interest in Hepatology. Ashok spent 12 months at the New Zealand Liver Transplant Unit under the supervision of Professor Ed Gane, followed by a clinical fellowship in Hepatology at the Princess Alexandra Hospital, Brisbane, Australia under Dr Katherine Stuart.

Dr Raj has a number of publications and presentations to national and international meetings and was awarded a young Investigator award at the 17th annual Coolum update in Gastroenterology and Hepatology in 2013.

Ashok has commenced PhD studies with the University of Queensland investigating the role of intestinal mucosal permeability and gut microbiota in the pathogenesis of chronic liver disease.

Dr Rebecca Ryan, BMBS (Hons), FRACP

Dr Rebecca Ryan is has had an appointment as staff Gastroenterologist and Hepatologist since 2007. In addition to having a major interest in Liver Transplantation and being a member of the Queensland Liver Transplant Service, Dr Ryan has a strong interest in Viral Hepatitis.

Rebecca obtained her medical degree from the Flinders University of South Australia in 1998, graduating with Honours. She undertook physician training at the Royal Adelaide Hospital (RAH) in Adelaide, and completed her gastroenterology training at the Princess Alexandra Hospital (PAH) in 2006 before embarking on a clinical fellow year at Greenslopes Private Hospital. Dr Ryan currently works as a Staff Specialist at the PAH, and in private practise at Montserrat Day Hospitals.

Dr Caroline Tallis, BPhty (Hons), MBBS) (Hons), FRACP

Dr Tallis is a consultant Gastroenterologist and Hepatologist at The Princess Alexandra Hospital in Brisbane where she has a strong interest in Liver Transplantation, being a member of The Queensland Liver Transplant Service.

After graduating form the University of Queensland with a Bachelor of Physiotherapy (Hons) degree, Caroline completed her MBBS (Hons) at the University of Sydney. This was followed in 2010 by a position as the Clinical Hepatology and Liver Transplant Fellow at The Princess Alexandra Hospital where she developed an interest in Liver Transplantation. The following year she travelled to the UK where she held the position of Clinical Research Fellow at the Institute of Liver Studies at Kings College Hospital, London, United Kingdom.

Caroline sits on the Australian Liver Association executive committee, ILTS vanguard committee, APASL annual meeting organising committee, GESQ executive.

Dr Terrance Tan, PhD, MBBS, FRACP

Dr Terrence Tan graduated in medicine from the University of New South Wales in 1999 and has trained in gastroenterology and hepatology throughout different centres in Western Australia and Queensland. Dr Tan performs diagnostic and therapeutic endoscopy and has a broad interest in general gastroenterology and hepatology. He completed his PhD in 2012 investigating the regulation of iron signalling in chronic liver disease. Dr Tan also has clinical sessions at the Department of Gastroenterology and Endoscopy Services of Queen Elizabeth II Jubilee Hospital.

Associate Professor Linda Fletcher, BSc (Hons), PhD

Associate Professor Fletcher is the Senior Scientist in the Gastroenterology & Hepatology Department at The Princess Alexandra Hospital, and is an academic title holder with the University of Queensland. She obtained her undergraduate degrees at the University of Natal, South Africa. Following a Scientist position in the Gastroenterology Unit at the Royal Postgraduate Medical School Hammersmith Hospital London, UK, Linda obtained her PhD whilst working in the Liver Unit at the Queensland Institute of Medical Research. She joined the Gastroenterology and Hepatology Unit at the Princess Alexandra Hospital in 1998 and established the Unit’s research laboratories with Professor Darrell Crawford, the then Director.

Linda contributes to clinical services in the department by conducting ambulatory 24hr oesophageal pH monitoring and facilitating BRAVO pH testing. She also performs non-invasive 13C breath tests for gastrointestinal and liver function.

Her major research interest focuses on iron, alcohol and fat as co-toxins in liver disease in promoting accelerated fibrogenesis. She has been a chief investigator on a number of NHMRC project grants and has attracted funding from the Queensland Smart State Project grant scheme, and has supervised a number of PhD candidates. Linda has published over 50 scientific peer reviewed papers including the specialist journals Gastroenterology, and Hepatology and co-authored 4 book chapters.

Gastroenterology and Hepatology at other hospitals and centres

Last updated 1 May 2018
Last reviewed 21 May 2015