Princess Alexandra Hospital's Colorectal Unit provides a comprehensive colorectal surgery service to the south Brisbane region.

Princess Alexandra Hospital also offers surgery to some patients with either primary peritoneal malignancies or secondary cancers arising from the appendix, colon, rectum or small bowel.

Surgeons from the Colorectal Unit participate in aid work in third world countries, with the aim of upskilling local doctors and providing life changing treatments for residents.